ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors
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چکیده
منابع مشابه
ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors.
NAC (N-acetyl-L-cysteine) is commonly used to identify and test ROS (reactive oxygen species) inducers, and to inhibit ROS. In the present study, we identified inhibition of proteasome inhibitors as a novel activity of NAC. Both NAC and catalase, another known scavenger of ROS, similarly inhibited ROS levels and apoptosis associated with H₂O₂. However, only NAC, and not catalase or another ROS ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2013
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj20130282